Type 1 diabetes definition These include cardiovascular disease (doubled risk), chronic renal failure (the main cause of dialysis in developed world adults), retinal damage (which can lead to blindness and is the most significant cause of adult blindness in the non-elderly in the developed world), nerve damage (of several kinds), microvascular damage (including erectile dysfunction (impotence) and poor healing which can lead to gangrene and even amputation -- the leading cause of non-traumatic amputation in developed world adults). Pancreas transplants are not generally remended because introducing a new, functioning pancreas to a patient with diabetes can have negative effects on the patient's normally functioning kidney. Vitamin D in doses of 2000 IU per day given during the first year of a child's life has been connected in one study in Northern Finland (where intrinsic production of Vitamin D is low due to low natural light levels) with a reduction in the risk of getting type I diabetes later in life (by 80%) [6]. Geic factors, usually polygenic, are present in most patients. A subtype of type 1 (identifiable by the presence of antibodies against beta cells) typically develops slowly and so is often confused with Type 2. Thirst develops because of osmotic effectsaŹ"sufficiently high glucose (above the "renal threshold") in the blood is excreted by the kidneys, but this requires water to carry it and causes increased fluid loss, which must be replaced. The fraction of type 2 diabetics in other parts of the world varies substantially, almost certainly for environmental and lifestyle reasons, though these are not known in detail. Currently, type 1 is treated with insulin replacement therapy, carbohydrate counting and careful monitoring of blood glucose levels using Glucose meters. The World Health Organization recognizes three main forms of diabetes: type 1, type 2 and gestational diabetes (or type 3, occurring during pregnancy) [1], although these share signs and symptoms but have different causes and population distributions. Type 1 diabetes definition. Diabetes mellitus type 2 is often associated with obesity and hypertension and elevated cholesterol (bined hyperlipidemia), and with the condition Metabolic syndrome (also known as Syndrome X, Reavan's syndrome, or CHAOS). Examples include diabetes mellitus caused by hemochromatosis, pancreatic insufficiency, or certain types of medications (e.g. long-term steroid use). Diabetes mellitus with a known etiology, such as secondary to other diseases, known gene defects, trauma or surgery, or the effects of drugs, is more appropriately called secondary diabetes mellitus. Type 1 diabetes definition. Type 1 diabetes definition
The American Diabetes Association funds some work on Type I, but also devotes much of its resources to Type II Diabetes. Vacor (N-3-pyridylmethyl-N'-p-nitrophenyl urea), a rodenticide introduced in the United States in 1975, selectively destroys pancreatic beta cells, resulting in Type 1 diabetes after accidental or intentional ingestion. The classical triad of diabetes symptoms is polyuria (frequent urination), polydipsia (increased thirst, and consequent increased fluid intake) and polyphagia (increased appetite). |